Infertility is called unexplained when a couple has been having regular intercourse without conceiving, and standard tests (ovulation, fallopian tubes, uterus and semen analysis) are all normal. It accounts for about a quarter of infertile couples. Several factors are thought to contribute, and research continues to uncover new causes.
Weight and fertility
People with a high body mass index (BMI) are more likely to have difficulty conceiving than those of normal weight. Women with obesity are more prone to ovulation and hormonal disorders, respond less well to fertility drugs and often need higher doses. If pregnancy happens, the risks of miscarriage, high blood pressure, gestational diabetes and preterm birth are higher. Losing even 5–10% of body weight can restore ovulation and improve the chance of pregnancy. Being significantly underweight can also stop ovulation.
Stress and fertility
Infertility itself is stressful, and pressure from family and society adds to it. In men, psychological factors can cause erectile problems, premature ejaculation or absent ejaculation. In women, severe stress can disturb ovulation, and anxiety can cause vaginal muscle spasm (vaginismus) that makes intercourse painful. Stress is rarely the only cause of infertility, but support and counselling are an important part of care.
Treatment options
Current guidelines recommend a stepwise approach based mainly on the woman’s age and how long the couple has been trying: a period of expectant management for younger couples, ovarian stimulation with intrauterine insemination (IUI), and IVF, which offers the highest pregnancy rate per cycle and also reveals problems with egg or fertilization that standard tests cannot detect.
International Guidelines
In line with global standards, Dr. Sabry follows the latest recommendations from the American Society for Reproductive Medicine (ASRM), European Society of Human Reproduction and Embryology (ESHRE), and Royal College of Obstetricians and Gynaecologists (RCOG). Thus, patients receive care that is safe, ethical, and evidence-based.
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Why Choose Dr. Ashraf Sabry?
Dr. Ashraf Sabry, consultant in obstetrics, gynecology, fertility, and aesthetic gynecology, is recognized among the best OBGYN and fertility specialists in Cairo. With over 20 years of experience, he combines science and compassion to provide world-class care. Book your appointment through the contact page, WhatsApp, or call +201022224442.