In some people, the immune system produces antibodies against sperm. These antisperm antibodies can coat sperm, reduce their movement and interfere with fertilization, which can delay pregnancy. In men, they usually follow injury, infection or surgery of the reproductive tract, a blocked sperm duct, or a reversed vasectomy.
It was once thought that antibodies in the woman’s cervical mucus were a common cause of infertility. Current evidence shows that routine antibody testing in women, and the post-coital test once used to look for it, do not help in planning treatment, so they are no longer recommended.
Treatment
When antisperm antibodies are significant, the most effective treatment today is ICSI (intracytoplasmic sperm injection), where a single sperm is injected directly into each egg, bypassing the antibodies’ effect on sperm movement and binding. Steroid treatment, used in the past, is no longer favoured because of its side effects and limited benefit.
International Guidelines
In line with global standards, Dr. Sabry follows the latest recommendations from the American Society for Reproductive Medicine (ASRM), European Society of Human Reproduction and Embryology (ESHRE), and Royal College of Obstetricians and Gynaecologists (RCOG). Thus, patients receive care that is safe, ethical, and evidence-based.
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Why Choose Dr. Ashraf Sabry?
Dr. Ashraf Sabry, consultant in obstetrics, gynecology, fertility, and aesthetic gynecology, is recognized among the best OBGYN and fertility specialists in Cairo. With over 20 years of experience, he combines science and compassion to provide world-class care. Book your appointment through the contact page, WhatsApp, or call +201022224442.