دراسة الجينات

Gender Selection Before Embryo Transfer

Gender selection (family balancing) identifies the sex of embryos created through IVF before they are transferred to the uterus, so that only embryos of the desired sex are transferred.

Embryos are grown to the blastocyst stage (day 5). A laser makes a small opening in the embryo’s outer shell and a few cells are taken from the outer layer, which later forms the placenta. The cells are analysed by next-generation sequencing (NGS), which reads all 23 pairs of chromosomes, including the sex chromosomes: XX for a girl and XY for a boy. The embryos are frozen while results are awaited, and a chromosomally normal embryo of the desired sex is transferred in a later cycle.

Chromosome analysis of an embryo

Accuracy and limits

Sex identification with NGS is more than 99% accurate. The older FISH method, which tested a single cell from a day-3 embryo, has been replaced because it was less reliable. What PGT cannot guarantee is that embryos of the desired sex will be available: this depends on how many eggs are collected, how many reach the blastocyst stage and how many are chromosomally normal, which is strongly affected by the woman’s age. A frank discussion of realistic chances before starting is essential.

Learn more about our program on the IVF gender selection page.


International Guidelines

In line with global standards, Dr. Sabry follows the latest recommendations from the American Society for Reproductive Medicine (ASRM), European Society of Human Reproduction and Embryology (ESHRE), and Royal College of Obstetricians and Gynaecologists (RCOG). Thus, patients receive care that is safe, ethical, and evidence-based.

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Why Choose Dr. Ashraf Sabry?

Dr. Ashraf Sabry, consultant in obstetrics, gynecology, fertility, and aesthetic gynecology, is recognized among the best OBGYN and fertility specialists in Cairo. With over 20 years of experience, he combines science and compassion to provide world-class care. Book your appointment through the contact page, WhatsApp, or call +201022224442.

This chapter is for medical education and does not replace an examination and consultation with your doctor.

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IVF, gender selection, IntimiPlasty™ and complete OB/GYN care.